3R method

Whooping cough vaccine safety

Check out our new publication on a novel alternatives-to-animals method to detect residues of active pertussis toxin (causing Whooping cough) in anti-whooping cough vaccine. Identification of biomarkers to detect residual pertussis toxin using microarray analysis of dendritic cells. Vaessen SF,

3R methods

One of the most important spin-offs of our current research is the development of methods potentially suitable to replace or reduce the use of animals in Life Sciences. Animal experiments in science are necessary to gain mechanistic insight into biological processes, to assess (risk to) hazard of potentially harmful effects of chemicals and pharmaceuticals to humans and animals, and to ascertain the potency and safety of biologicals and vaccines. Every animal experiment performed in the Netherlands is done under rules and regulations that are decribed in the Dutch Act on the Welfare and Use of Animals for Sciences (Wet op de Dierproeven en Het Dierproevenbesluit). Currently, national laws of all the member states of the European Union are being revised and brought in line with the new EU Directive on on the protection of animals used for scientific purposes.