Antibody mediated allergy to Cow's milk can form a major threat to the infant's health. Infants with this type of allergy cannot consume normal milk from cow origin. Cow’s milk-derived whey hydrolysates are nutritional substitutes for children with this type of allergy. These hydrolysates can be regarded as degraded proteins of which the fragments will no longer to be recognized by the immune system of the allergic child. Cow's milk (or more specifically whey) hyrolyses therefore, will not trigger an allergic reaction. For the safety of the infant it is important to assess any residual allergenicity of the hydrolyses, before using these in infant food.
Het begon drie jaar geleden met acht spaarvarkens, en mondde uit in mondiale aandacht: het project Sneller van Innovatie naar Mens (SLiM), opgezet om de implementatie van alternatieven voor dierproeven te versnellen en daarmee innovatie aan te jagen. In nauwe samenwerking tussen onderzoekers, het bedrijfsleven en overheidsinstellingen zoals RIVM en CBG. Alleen zo bereik je resultaten...
Check out this new video on the SIA RAAK-PRO project 'NAT-TEST'. The movie provides back ground on the project, the collaboration with partners and our research group. This movie has been produced by Regieorgaan Stichting Innovatie Alliantie who awarded our RAAK PRO 'NAT-TEST' project with the RAAK Award 2013.
The SLiM project was concluded with a symposium on January 16th 2014. Over 100 representatives from industry, regulatory bodies, knowledge institutions and research & academic organizations were present during the presentations on the progress made in the SLiM project over the past three years. The full report on the symposium can be viewed and downloaded in pdf in this article.
Marie-Jean Schiffelers, PhD candidate at the Utrecht University School of Governance (USBO) distilled the most important drivers and barriers that act upon regulatory acceptance of 3R methods. The conclusions have been summarized in a workshop report, published as an article in Regulatory Toxicology and Pharmacology.