INT presented at WC10!

Innovative Testing in Life Sciences & Chemistry (INT) was well presented at the 10th World Congress on Alternatives and Animal Use in the Life Sciences in Seattle, Washington, USA from August 20 to 24, 2017.  We delivered a well-received oral presentation on the work we are currently doing using intestinal stem cell derived organoids. We showed that all intestinal cell types are present in organoids. Regional-specificity is maintained and that thse organoids can be cultured into a two-dimensional intact intestinal layer which is of particular interest if you want to test for example absorption of compounds.

Furthermore, we presented 3 posters on different ongoing projects. One poster was about our participation in the IMI project Vac-2-Vac,  a collaborative research project which aims to develop and validate quality testing approaches for both human and veterinary vaccines using non-animal methods. We showed our progress in using a kinomics approach towards a safety assay for live attenuated pertussis toxin vaccines. Secondly, we presented a poster on the bicycle ergometertest: a human stress model to test nutritional effects on intestinal function and immune responsiveness, the ongoing PhD research project of Shirley Kartaram. Finally, we showed on the third poster the outlines and requirements for the VitalTissue initiative, a fresh human tissue supply chain to enable translational research in the Netherlands.

Besides presenting ourselves and our project data, we learned the latest technologies for reduction and replacement of animals, we heard about innovations in approaches to ethics, animal welfare, public policy and education such as Green Chemistry. Furthermore we talked with fellow scientists and companies about science, possibilities to work together and social events.

If you were not able to visit WCA10 or missed us and want to know more about our projects, please don’t hesitate to ask for more information:

Read or download the presented posters in pdf below:

Authors: Stefan Vaessen & Cyrille Krul, 2017