Associate professor Teunis is currently leading several applied research projects on development and validation of innovative alternative methods that contribute to reduction and replacement of animal testing. Next to a primary role in managing projects, Teunis is also coaching people in the group. Core tasks are writing scientific articles and grant proposals; reports and texts for marketing and public relations purposes; supervising students; human resources and project acquisition and dissemination of research results and methods into Educational programs. Teunis also has a teaching position at the Institute for Life sciences & Chemistry where he teaches in Immunology; Toxicology and Alternatives to Animal Use. Furthermore he supervises internship-students and co-ordinates post-graduation courses and summer courses. Teunis completed his Ph.D. in 2003 which was performed at Wilhelmina's Children's Hospital in Utrecht, where he worked on brain-immune inteactions and tumor angiogenesis. His Master's degree was obtained at the Faculty of Biology in Utrecht where he specialised in animal physiology and neurosciences.
Currently, Teunis is involved in a number of Data Science activities. The main tools that are used for this aspect of the group's research are the Statististical Programming Language R, Git, RStudio and Bioconductor. Teunis is also a teaching professor for several R-programming modules in the Institute for Life Sciences & Chemistry. He is key user for R and RStudio at HU and his current research focuses on applied predictive modelling for toxicology and text mining. Furthermore, he develops R-packages for publications of the group. Most of the packages can be found on the HU github page: https://github.com/uashogeschoolutrecht
Short-List of publications:
1. grintar: A demonstration of reproducible analysis, visualization and distribution of ergometer exercise data, Teunis et al., Conference Abstract, USER!, Brussels, July 3-7.
2. Transfer of a two-tiered keratinocyte assay: IL-18 production by NCTC2544 to determine the skin sensitizing capacity and epidermal equivalent assay to determine sensitizer potency. Teunis, M.A.T. et al., Toxicol. in Vitro. 2012.
3. Alternatives to Animals, Teunis, M.A.T., International Innovation, April, 2013
4. Pre-validatie voor duidelijkheid toepasbaarheid nieuwe 3V-testmethoden, Teunis, M.A.T., Website NKCA, 2013
5. Reduced tumor growth, experimental metastasis formation, and angiogenesis in rats with a hyperreactive dopaminergic system. Teunis, M.A.T. et al., FASEB J. 2002.
6. Changes in innate and acquired immune responses in mice with targeted deletion of the dopamine transporter gene. Kavelaars, A. et al., J. Neuroimmunol. 2005.
7. Maternal deprivation of rat pups increases clinical symptoms of experimental autoimmune encephalomyelitis at adult age. Teunis, M.A.T. et al., J. Neuroimmunol. 2002.